Mauricio C.D.F. Xavier, Daiane M. Xavier, Natália Seus, Eder J. Lenardão, Gelson Perin and Diego Alves Pages 14 - 23 ( 10 )
We describe here a simple and rapid protocol for the synthesis of (arylselanyl)phenyl-1H- 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions using Microwave Irradiation. The products were obtained under mild conditions in excellent yields in a short reaction time by reacting azidophenyl arylselenides with a range of terminal alkynes using catalytic amount of Cu(OAc)2.H2O/sodium ascorbate. This Click Chemistry protocol is an efficient method to synthesize new selenium compounds with potential application in biological studies and materials sciences.
Alkynes, azides, catalysis, 1, 3-dipolar, click chemistry, copper, cycloaddition, green chemistry, heterocycles, microwave, 1, 2, 3-triazoles, nitrogen compounds, selanyltriazoles, selenium compounds.
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