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Microwave Assisted Reactions of 5-Amino-1, 3-disubstituted Pyrazoles with Some Benzaldehydes

[ Vol. 3 , Issue. 2 ]

Author(s):

Agnieszka Puchala, Magdalena Marcinkowska and Danuta Rasala   Pages 97 - 101 ( 5 )

Abstract:


The microwave-promoted reactions of 5-amino-1,3-disubstituted pyrazoles with benzaldehyde, 4-chloro- and 4-nitrobenzaldehydes are presented. The use of microwave irradiation with variable input power leads to different products, such as Schiff bases, diamine derivatives and bispyrazolo[ 3,4-b;4’3’-e]pyridines in moderate to excellent yields and high purities.

Keywords:

Aldehydes, bis-pyrazolo[3, 4-b;4’, 3’-e]pyridines, diamine derivatives, N-heterocycles, microwave assisted synthesis, pyrazoles.

Affiliation:

Institute of Chemistry, Jan Kochanowski University, Swietokrzyska 15G, 25-406 Kielce, Poland.



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